Administration

M. Eileen Dolan, PhD, Professor of Medicine, Section of Hematology/Oncology; Chair, Committee on Clinical Pharmacology and Pharmacogenomics; Associate Director of Education, the University of Chicago Comprehensive Cancer Center and the Center for Personalized Therapeutics

Dr. Dolan is a pharmacologist working in the area of pharmacogenomics of anticancer agents. She is a leader in developing cell-based methods to identify genetic variants contributing to chemotherapeutic induced cytotoxicity through their effect on gene expression. Her laboratory is focused on identification of genetic variation contributing to chemotherapeutic response and toxicity using preclinical models and translating those findings into clinical trials.

Telephone:  773-702-4441

E-mail:  edolan@medicine.bsd.uchicago.edu

Mark Ratain, MD, Leon O. Jacobson Professor of Medicine; Director, Center for Personalized Therapeutics; Associate Director for Clinical Sciences, the University of Chicago Comprehensive Cancer Center; Chief Hospital Pharmacologist for the University of Chicago Medical Center

Dr. Ratain is a hematology/oncologist and clinical pharmacologist whose research activities include both pharmacogenetics and antineoplastic drug development. Interests include genetic and non-genetic factors affecting the therapeutic index of irinotecan, a drug active in colorectal cancer and other solid tumors, factors affecting the therapeutic index of epidermal growth factor receptor inhibitors, genetic variation in glucuronosyltransferases, and methodological issues relevant to anticancer drug development.

Telephone:  773-702-4400

E-mail:  mratain@medicine.bsd.uchicago.edu

Manish Sharma, MD, Assistant Professor of Medicine, Section of Hematology/Oncology; Associate Director, Committee on Clinical Pharmacology and Pharmacogenomics; and Member of the University of Chicago Comprehensive Cancer Center

Dr. Sharma joined the University of Chicago faculty in 2012 after completing fellowship training at the University of Chicago in hematology/oncology and clinical pharmacology and was board certified in clinical pharmacology in 2013. His research focuses on the use of advanced quantitative methods (pharmacometrics) to improve the development and use of anticancer therapies.

Telephone:  773-834-0312

E-mail:  msharma@medicine.bsd.uchicago.edu

Michelle Domecki, BA is the Educational Manager for the Committee on Clinical Pharmacology and Pharmacogenomics. She has been with the University of Chicago since 1996 and has administered the training since 2000. She also participates in the administration of University of Chicago Comprehensive Cancer Center CURE and researcHStart programs as well as the graduate program in cancer disparities. Michelle has her B.A. in Social Science with a minor in Public Administration.

Telephone:  773-702-9699

E-mail:  mdomecki@uchicago.edu